TITLE:
Buruli Ulcer: Epidemiological, Clinical and Biological Profile of Patients in the Centre de Depistage et de Traitement d’Allada (Benin) from 2010 to 2014
AUTHORS:
Bérénice Dégboé, Christiane Koudoukpo, Mouhaéminath Alimi, Ghislain Emmanuel Sopoh, Fabrice Akpadjan, Roch Christian Johnson, Nadège Agbéssi, Hugues Adégbidi, Félix Atadokpèdé
KEYWORDS:
Buruli Ulcer, Epidemiology, Clinical Profile, Biological Confirmation, Benin
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.9 No.2,
April
4,
2019
ABSTRACT: Introduction: The objective of our work was to describe the epidemiological, clinical and biological profile of Buruli ulcer in “Centre de Dépistage et de traitement de l’ulcère de Buruli” (CDTUB) in Allada. Methods: A descriptive and retrospective study focused on new cases of Buruli ulcer received in the CDTUB of Allada from 2010 to 2014. The diagnosis of Buruli ulcer was based on epidemiological, clinical and biological arguments. Results: Over 5 years, 274 new cases of Buruli ulcer have been diagnosed. The average age of the patients was 12 years and the sex ratio was 0.8. The average time to first consultation was 45 days. Clinically, 61% had a joint functional limitation. Lesions were ulcerated in 69% of cases, category I (26%), category II (53%), category III (21%) and were present on the lower limbs in 57% of cases. Microscopy was positive in 65.7% of cases and PCR in 78.1% of cases. Microscopy supplemented by PCR confirmed the diagnosis in 81% of cases. Conclusion: The epidemiological, clinical and biological profile of Buruli ulcer in Allada was characterized by a predominant disease in children, a predominance of ulcerated forms and a decisive contribution of PCR to the diagnosis.