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Munoz-Torrero, D., Mangoni, A.A., Guillou, C., Collina, S., VandenEynde, J.J., Rautio, J., Keseru, G.M., Hulme, C., Chibale, K., Luque, F.J., Karaman, R., Gutschow, M., Liu, H. and Ragno, R. (2017) Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes. Molecules, 22, pii: E743.

has been cited by the following article:

• TITLE: Synthesis of Novel Heteropolycyclic Nitrogen Systems Bearing Fluorine Substituted Pyrazolo[3,4-d] Pyrimidine Derived from Polyfunctional π-Acceptor Compounds and Guanidine as Fungicidal Probes

  AUTHORS: Dina A. Bakhotmah, Salwa Y. Al-Hazme

  KEYWORDS: Synthesis Polyheterocyclic, Pyrazolo[3, 4-d] Pyrimidine, Antifungal

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.9 No.1, March 28, 2019

  ABSTRACT: Novel heteropolycyclic nitrogen systems bearing fluorine substituted pyrazolo[3,4-d] pyrimidine moiety have been synthesis by the interaction between N’-heteroaryl guanidine 4 with polyfunctional π-acceptors in different media and condition. The structures of the synthesis compounds were established by spectroscopic analysis and evaluated as antifungal probes in various concentration.