Article citationsMore>>

Mohan, R., Chou, Y.-L. and Morrissey, M.M. (1996) Pictet-Spengler reaction on solid support: Synthesis of 1,2,3,4-tetrahydro-β-carboline libraries. Tetrahedron Let- ters, 37, 3963-3966. doi:10.1016/0040-4039(96)00773-3

has been cited by the following article:

• TITLE: Syntheses and antimicrobial activities of amide derivatives of 4-[(2-isopropyl-5-methylcyclohexyl)oxo]-4-oxobutanoic acid

  AUTHORS: Auj e Sana, Sher Wali Khan, Javid H. Zaidi, Nida Ambreen, Khalid Mohammed Khan, Shahnaz Perveen

  KEYWORDS: Chiral 4-[(2-isopropyl-5-methylcyclohexyl)- oxo]-4-oxobutanoic Acid; Substituted Anilines;Amides; Antimicrobial Activity

  JOURNAL NAME: Natural Science, Vol.3 No.10, October 21, 2011

  ABSTRACT: Chiral 4-[(2-isopropyl-5-methylcyclohexyl)oxo]-4-oxobutanoic acid reacts with substituted anilines to produce amides 1-6 in high yields. Resulted amides 1-6 were investigated for their antifungal and antibacterial activities. Compounds 2 (96.5%) against Aspergillus fumigatus and 6 (93.7%) against Helminthosporium sativum demonstrated excellent activities. However, compounds 3 (37.6%) against Bacillus subtilis, 4 (33.2%) against Pseudomonas aurignosa, 5 against Klebsiella pneumonia demonstrated excellent growth inhibition potential.