TITLE:
Correlation between the Laboratory Test Results and Knee Functional Improvement of Pre- and Post-Total Knee Replacement Operation
AUTHORS:
Naranbat Lkhagvasuren, Puntsag Chultemsuren, Munkhbaatar Dagvasumberel, Anujin Batbold, Zolbayar Baasanjav, Battulga Khaltar, Otgonsaikhan Nomkhondorj, Batsukh Ombogo, Erdenebileg Avirmed, Avirmed Amgalanbaatar, Munkhbayarlakh Sonomjamts
KEYWORDS:
TUG, WOMAC, VAS, WHO
JOURNAL NAME:
Open Journal of Orthopedics,
Vol.9 No.3,
March
11,
2019
ABSTRACT: Objective: This study aimed to identify correlations of laboratory test results and knee joint function between pre- and post-operation of knee joint replacement surgery. Methods: The study covered 60 - 75 aged 50 patients who had operated with knee replacement surgery. 25 patients were male and another 25 patients were female. We compared laboratory test results of pre- and 3rd, 7th and 14th day of post-operation. Moreover, pre-operation knee joint function was compared with 3rd, 7th, 14th and 30th day of post-operation. Furthermore, we investigated the relationship among WBC, hemoglobin and function tests. Pre- and post-operative knee joint function tests were conducted by WOMAC (The Western On-tario and McMaster Universities Osteoarthritis), VAS (Visual Analogue Scale), TUG (Time up and Go) score, and MMT (Muscle Manual Test). Results: In pre-operation, patients’ average WBC was 6.447 ± 2.115 cells/μL, monocyte was 6.554 ± 3.101 cells/μL, lymphocyte was 31.177 ± 9.512 cells/μL and C-reactive protein was 0.6205 ± 0.922 mg/dL. In 3rd day of post-operation, WBC was 8.901 ± 2.869 cells/μL, monocyte was 4.881 ± 2.332 cells/μL, lymphocyte was 17.048 ± 9.702 cells/μL and C-reactive protein was 4.2762 ± 2.293 mg/dL. There was a statistically significant difference reported on pre- and post-operation pain, stiffness and daily activity (P rd day of post-operation were raised up and they were statistically significant (P rd, 7th, 14th day of TUG score was significantly correlated (P Conclusion: Results of WBC, hemoglobin, hematocrit, total protein, total bilirubin, and creatinine had increased in 3rd and 7th day of post-operation and had stabilized from 14th day of post-operation. Stiffness and TUG performance were controversially correlated in 3rd, 7th, 14th, 30th day of post-operation. However, in 7th and 14th of post-operation, patients’ muscle strength and knee joint amplitude had become stabilized and improved from 30th day of post-operation. Moreover, after the operation, the number of WBC controversially affected patients’ mobility. In addition, we found that as hemoglobin and red blood cells increased, walking ability improved as well.