TITLE:
Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents
AUTHORS:
Wafa A. Baker Bawazir
KEYWORDS:
Thioethers, Thiazolidnones, 1, 2, 4-Triazino Indole, Fungicidal, Cycloaddition
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.9 No.1,
March
11,
2019
ABSTRACT: Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.