TITLE:
Huge Sacrococcygeal Teratoma in an Adult Female: A Case Report
AUTHORS:
Yasutake Uchima, Naoki Aomatsu, Takuma Okada, Hironari Miyamoto, Gen Tsujio, Shigeaki Kurihara, Toshiki Hirakawa, Takehiko Iwauchi, Junya Morimoto, Kazuhiro Takeuchi
KEYWORDS:
Sacrococcygeal Teratoma, Adult, Surgical Treatment
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.3,
February
28,
2019
ABSTRACT: Background: Teratomas are a type of germ cell tumor, which are mostly benign, and
dominative in adult females. Sacococcygeal teratomas are usually found in
newborns or children, and can be detected prenatally; they are exceedingly rare
in adults. We reported a case of a sacrococcygeal teratoma in adult female. Case
presentation: A 26-year-old female was diagnosed with a presacral tumor 6
years ago. Pelvic computed tomography (CT) demonstrated a presacral
heterogeneous tumor, containing multi-located
cystic area and enhanced solid component with calcification. Magnetic resonance
imaging (MRI) showed a presacral non-enhanced cystic lesion with solid
component, 128 mm × 104 mm × 102 mm, which was suspected of having invaded the
rectal wall, fifth sacral vertebra (S5), and coccyx. She underwent abdomino-sacral total
excision of tumor with coccygectomy. Histopathological examination revealed a
tumor with intricate admixture of ectodermal (epidermis, sebaceous glands and
squamous), mesenchymal (cartilage, adipose tissue, blood vessels, nerves and
skeletal muscle) and endodermal components (respiratory
epithelium and intestinal epithelium) respectively. After 24 months
of follow-up the patient was both clinically and radiologically disease free. Conclusions: Early
complete excision was the preferred definitive modality of treatment for sacrococcygeal
teratoma, and multi-staged excision and reconstruction resulted in successful
and safe treatment in our case.