TITLE:
Multi-Drug Resistance Pattern of Lactose Non-Fermenting Escherichia coli as Causative Agent of Urine Tract Infections in Luanda, Angola
AUTHORS:
Aleksey Shatalov
KEYWORDS:
Escherichia coli, Multi-Drugs Resistance (MDR), Lactose Non-Fermenting, Urine Tract Infections, Colony Forming Unit (CFU)
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.9 No.1,
January
28,
2019
ABSTRACT: This prospective study was carried out to assess the sensitivity and resistance pattern of lactose non-fermenting Escherichia coli from July 2018 to December 2018 in the Laboratory of Microbiology at Luanda Medical Center, Angola. Out of 1170 patient, a total of 120 urine specimens infected with Escherichia coli (>105 CFU/ml) were collected according to the routine protocol of urinalysis. Among these 120 isolates, 25 (21%) isolates were determined as “atypical”, lactose non-fermenting E. colis trains. The twenty-five lactose non-fermenting Escherichia coli strains isolated from urine samples in Luanda Medical Center were declared as Multiple Drugs-Resistant strains with high resistance to Cefalexine (100%), Cefuroxime (100%), Ceftriaxone (92%), Gentamycin (92%), Ciprofloxacin (72%) and Amoxiciclin/Clavulanic (80%). The alarming resistance level to the first-choice drugs for the treatment of urinary tract infections caused by non-fermentative lactose E. coli was observed.