TITLE:
Abdominoperineal Resection in Rectal Cancer in General Surgery Department at Gabriel Toure University Hospital
AUTHORS:
Amadou Traore, Abdoulaye Diarra, Madiassa Konate, Souleymane Thiam, Soumaila Keita, Tani Kone, Boubacar Karembe, Assitan Kone, Boubacar Sidibe, Amadou Bah, Amadou Maïga, Ibrahim Diakite, Bakary Tientigui Dembele, Alhassane Traore, Adegne Togo, Lassana Kante, Moussa Samake, Moustapha Issa Mangane, Thierno Madane Diop, Mamadou Salia Diarra, Adama Diakite, Gangaly Diallo
KEYWORDS:
Abdominoperineal, Cancer, Mali, Rectum, Resection, Surgery
JOURNAL NAME:
Surgical Science,
Vol.10 No.1,
January
16,
2019
ABSTRACT: The objectives: Were to determine the hospital frequency of abdominoperineal resection (APR); to determine mortality and morbidity rates and to assess oncologic outcomes. Method and patients: We performed a retrospective study between 2008 and 2013 in general surgery department at Gabriel Toure University Hospital (UH) which included all patients admitted for rectal cancer confirmed by pathological examination, and having undergone an APR. Results: We have collected 17 cases which accounted for 65.38% of curative resections of rectal cancer. The sex-ratio was 0.89 and the averageage was 49.53 years. The average tumor distance from the anal verge was 4.59 ± 1.7 cm. All patients had adenocarcinoma of the rectum. The histopathologic grade was well in 7 cases, moderate and poor in 5 cases each. According to the pathologic TNM classification, 13 patients were classified T4, 14 patients N+. APR was associated with hysterectomy and partial colpectomy in 4 cases. The average duration of interventions was 202.06 ± 25.68 minutes. The average duration of hospitalization was 18.24 ± 04.89 days. The postoperative mortality and morbidity rates were 5.88% and 29.42%, respectively. Local recurrence was observed in 6 patients and liver metastasis in 2 patients. The overall survival rate was 37.5% at 2 years and 18.75% at 5 years. Conclusion: APR still occupies an important place in our practice. Our results could be improved by the recent introduction of neoadjuvant radio chemotherapy in Mali.