Article citationsMore>>
újhelyi, M., Pukancsik, D., Kelemen, P., Sávolt, á., Godény, M., Kovács, E., Udvarhelyi, N., Bak, M., Polgár, C., Rubovszky, G., Kásler, M. and Mátrai, Z. (2016) Breast Cancer Care Quality Analysis of the National Institute of Oncology in Hungary According to the Requirements of European Society of Breast Cancer Specialists (EUSOMA). Hungarian Medical Journal, 157, 1674-1682.
has been cited by the following article:
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TITLE:
A Single Centre Experience with Phenotype Dependent Perioperative Chemotherapy for Primary Breast Cancer
AUTHORS:
Tamás Kullmann, Kofi Agyemang-Prempeh, Adél Ambrus, Gabriella Herodek, Balázs Hillier, Károly Kocsis, Ilona Laszip, Mária Mák, Tamás Pintér, István Sipőcz
KEYWORDS:
Breast Cancer, Carboplatin, Trastuzumab, Adjuvant, Neoadjuvant
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.10 No.1,
January
4,
2019
ABSTRACT: Background:
Standard adjuvant or neo-adjuvant chemotherapy of primary breast cancers
consists of docetaxel and the combination of anthracyclin-cyclophosphamide
in two steps. According to international literature, the neo-adjuvant treatment of triple negative
tumours by the combination of docetaxel-carboplatin allows a high rate of
pathological complete remission and the adjuvant treatment of small, node
negative HER2+ tumours by the combination of paclitaxel-trastuzumab allows a
negligible recurrence rate together with a very good tolerance. Methods: Our
aim was the retrospective analysis of the alternative chemotherapy regimens in
our patient population. Results: The neo-adjuvant docetaxel-carboplatin allowed
a 55% pathological complete remission rate among 20 patients. With the adjuvant
paclitaxel-trastuzumab, we did not notice any recurrence among 5 patients
at a median follow-up of 18 months. Conclusion: Our results correspond
to the literature data. The spread of the protocols in the clinical practice is
proposed.