TITLE:
Yacon Product (PBY) Modulates Intestinal Constipation and Protects the Integrity of Crypts in Wistar Rats
AUTHORS:
Mônica de Souza Lima Sant’Anna, Vivian Carolina Rodrigues, Tatiane Ferreira Araújo, Tânia Toledo de Oliveira, Maria do Carmo Gouveia Pelúzio, Célia Lúcia de Luces Fortes Ferreira
KEYWORDS:
Prebiotic, Yacon, Single Chain Fatty Acid, Constipation
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.9 No.12,
December
28,
2018
ABSTRACT: This study investigated the use of a product based on yacon (PBY) in microbiological, physical-chemical and intestinal characteristics of Wistar rats artificially constipated with Loperamide®. Thirty-two rats were divided into four groups: Control (C), Constipated Control (CC), PBY (not constipated) and Constipated PBY (PBYC). The dosage of 0.14 g of FOS+ inulin/kg was tested. Microbiota, pH and faeces characteristics of faeces and caecal contents were evaluated. Caecal weight, morphometry of caecal villi and the concentration of short-chain fatty acids were determined. Higher caecal weight was identified in the PBYC animals as well as higher width, height and depth of cripts. The PBY group showed the highest (p