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Franks, S., Gharani, N., Waterworth, D., Batty, S., White, D., Williamson, R. and McCarthy, M. (1997) The Genetic Basis of Polycystic Ovary Syndrome. Human Reproduction, 12, 2641-2648.
https://doi.org/10.1093/humrep/12.12.2641

has been cited by the following article:

• TITLE: Studying the Effect of Laparoscopic Ovarian Drilling on Ovarian Reserve via Measurement of Anti-Mullerian Hormone in Polycystic Ovarian Syndrome Patients

  AUTHORS: Sherif Gaafar, Fady M. Shawky Moiety, Hadir Ward, Youssry Mohey Eldin

  KEYWORDS: Polycystic Ovarian Syndrome, AMH, LOD

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.8 No.14, December 27, 2018

  ABSTRACT: Background: Polycystic ovarian syndrome (PCOS) is the most common cause of anovulation and it also causes other metabolic and endocrinal disorders. Lines of management of PCOS include several medical options in addition to laparoscopic ovarian diathermy (LOD). However, the effect of LOD on ovarian reserve has always been a concern. Advocates to LOD claimed that the decrease in ovarian reserve following LOD is merit not a drawback. Study Design: A case series study aimed at investigating the effect of LOD on Anti-Mullerian hormone (AMH) and trying to find the relation between AMH levels and success of LOD. Patients and Methods: The study was carried out on 30 clomiphene citrate resistant PCOS patients from EL Shatby maternity hospital. Hormonal profile including; FSH, LH, free testosterone, AMH and progesterone was done preoperatively and 3 months after LOD. Results: After LOD 19/30 cases (63.3%) had spontaneous ovulation. After LOD the mean AMH decreased significantly from 9.12 ng/ml to 7.66 ng/ml (p = 0.006*). Responders had significantly lower preoperative AMH as compared to non-responders (8.01 ng/ml Vs 10.01 ng/ml). Responders had a highly significant (p Conclusion: Measurement of serum AMH concentration before LOD may be a useful tool in predicting responders to LOD and help in patient selection.