TITLE:
Post-Infectious Acute Glomerulonephritis in Child: Epidemiological, Clinical and Evolutionary Aspects in Gabriel Touré Teaching Hospital in Mali
AUTHORS:
Mariam Sylla, Fatoumata Dicko-Traoré, Abdoul Karim Doumbia, Aminata Coulibaly, Abdoul Aziz Diakité, Modibo Sangaré, Pierre Togo, Fousseyni Traoré, Amadou Touré, Djènèba Konaté, Karamoko Sacko, Belco Maiga, Fatoumata Léonie Diakité, Lala N’Drainy Sidibé, Mohamed Elmouloud Cissé, Adama Dembélé, Hawa Diall, Oumar Coulibaly, Ibrahim Hamadou, Leyla Maiga, Issiaka Koné, Boubacar Togo, Toumani Sidibé
KEYWORDS:
Glomerulonephritis, Infection, Pediatrics, Mali
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.8 No.4,
December
26,
2018
ABSTRACT: Introduction: Acute post-infectious glomerulonephritis (APIGN) can be serious due to
its complications that still occur in our countries. In this work, we aimed to
study the epidemiological, clinical, biological and evolutionary aspects of
APIGN. Patients and methods: We conducted a retrospective, descriptive
study from January 1st, 2015 to December 31st, 2017 in
the pediatric ward of the Gabriel Touré
Teaching Hospital in Bamako. All children hospitalized for APIGN were included. Results: In two years, we included 10 children aged 7 years old on
average; all from low socioeconomic backgrounds. The sex ratio was 1.5. On average,
the children spent 15.8 days before our consultation. Edema was the main reason
for consultation. We found a history of infection and high blood pressure in
30% each, and renal failure in 10% of the children. Hematuria and proteinuria
were detected in 100% and 90%, respectively. Hypocomplementemia was observed in
66.6%. One third of the children had a positive antistreptolysin O. The average
duration of hospital stay was 11.2 days. The evolution was favorable in 90%. Kidney
failure was the leading cause of death. Conclusion: Acute post-infectious glomerulonephritis is still a
reality in our context. Emphasis should be put on its prevention by improving
the hygienic conditions, detection and the management of infections.