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Picascia, M., Pozzi, N.G., Todisco, M., Minafra, B., Sinforiani, E., Zangaglia, R., Ceravolo, R. and Pacchetti, C. (2018) Cognitive Disorders in Normal Pressure Hydrocephalus with Initial Parkinsonism in Comparison with de Novo Parkinson’s Disease. European Journal of Neurology..

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• TITLE: Mild Cognitive Impairment in Parkinson Disease: A Neuropsychological Study of 25 Patients

  AUTHORS: Siham Sanhaji, Mounia Rahmani, Maria Benabdeljlil, Mustapha El Alaoui Faris

  KEYWORDS: MCI, PD, Neuropsychological Study, Executive Functions, Episodic Memory, Visuospatial Capacities

  JOURNAL NAME: World Journal of Neuroscience, Vol.8 No.4, November 27, 2018

  ABSTRACT: Parkinson’s disease (PD) is associated with an increased incidence of cognitive impairment and dementia. Population-based cohort of 25 patients with incident PD underwent a large neuropsychological battery. Executive functions were the most affected cognitive domain including particularly initiation, mental flexibility and inhibition. Episodic memory and visuo-spatial functions were less affected. We found that 92% of patients were classified as having Mild Cognitive Impairment (MCI); most of them experienced PD-MCI Single-Domain (17 patients) with disturbances on executive functions. Less frequently, we identified a group of patients with multiple-domain PD-MCI demonstrating deficits on executive functions as well as on episodic memory and/or visuospatial capacities.