TITLE:
Mild Cognitive Impairment in Parkinson Disease: A Neuropsychological Study of 25 Patients
AUTHORS:
Siham Sanhaji, Mounia Rahmani, Maria Benabdeljlil, Mustapha El Alaoui Faris
KEYWORDS:
MCI, PD, Neuropsychological Study, Executive Functions, Episodic Memory, Visuospatial Capacities
JOURNAL NAME:
World Journal of Neuroscience,
Vol.8 No.4,
November
27,
2018
ABSTRACT: Parkinson’s disease (PD) is associated with an
increased incidence of cognitive impairment and dementia. Population-based
cohort of 25 patients with incident PD underwent a large neuropsychological
battery. Executive functions were the most affected cognitive domain including
particularly initiation, mental flexibility and inhibition. Episodic memory and
visuo-spatial functions were less affected. We found that 92% of patients were
classified as having Mild Cognitive
Impairment (MCI); most of them experienced PD-MCI Single-Domain (17 patients) with disturbances on
executive functions. Less frequently, we identified a group of patients with
multiple-domain PD-MCI demonstrating deficits on executive functions as well as
on episodic memory and/or visuospatial capacities.