TITLE:
Study of 41 Cases of Pregnancy after Uterine Leiomyoma Treatment by Uterine Artery Embolization (UAE)
AUTHORS:
Takahisa Kojima, Hidefumi Fujisawa, Kumiko Koyama
KEYWORDS:
Embolization, Gelatin Sponge Particles, Leiomyoma, Pumping Method, Uterine Artery Embolization (UAE), Uterine Leiomyoma, Pregnancy, Risk
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.8 No.13,
October
30,
2018
ABSTRACT: Uterine
leiomyoma, a benign tumor, may be treated with hormone therapy, conventional
surgical resection and uterine artery embolization (UAE): this paper reports
the study on safety after UAE treatment. Pregnancy
processes and prognoses of a total of 41 cases from 39 patients (two women were
pregnant twice) who succeeded to pregnancy after UAE treatment in our clinic
were studied. The average age of patients was 34.5 (29 - 40).
Patients included 24 cases of multiple uterine leiomyoma and 14 cases of
solitary leiomyoma; the average size of leiomyoma was 388.3 cm3 (15 - 1059 cm3) and the average period between UAE operation and
pregnancy was 26.5 months (1 - 120).
Causes of pregnancy were 29 cases of natural pregnancy and 12 cases of infertility
treatment: 28 cases succeeded in delivery, 7 cases resulted in spontaneous abortion,
and 6 cases are ongoing. Premature birth, placental abnormality and low-weight
babies were observed in 3, 3, and 1 cases, respectively; the latter 1 case was
of triplets. Although the incidence of placental abnormality was a little high,
no other serious complications were observed, suggesting that pregnancy after
UAE has no problem from the obstetric point of view. In the future, UAE is
considered to be worthwhile if carefully done for cases who want to become
pregnant.