Article citationsMore>>

Piel, F.B.M., Hay, S.I., Guta, S., Wealtherall, D.J., and Williams, T.N. (2013) Global Burden of Sickle Cell Anaemia in Children under Five, 2010-2050. Modelling Based on Demographics, Excess Mortality and Interventions. PLOS Medicine, 10, el001484.
https://doi.org/10.1371/journal.pmed.1001484

has been cited by the following article:

• TITLE: Sex Hormones Secretion Pattern in Pregnant Sickle Cell Subjects in Niger Delta Region, South of Nigeria

  AUTHORS: F. C. Ezeiruaku, E. M. Eze, C. U. Okeke

  KEYWORDS: Hormones, Progesterone, Estradiol, Sickle Cell, Secretion, Trimesters

  JOURNAL NAME: Open Journal of Endocrine and Metabolic Diseases, Vol.8 No.7, July 28, 2018

  ABSTRACT: Sickle cell anemia (SCA) patients are reported with infertility and low rate of pregnancies. This is associated with wide range of reproductive issues that are still relevant because of the complications and problems of the disease that still persist till date. This study was carried out to establish the secretion pattern of the sex hormones (Progesterone and Estradiol) in the three trimesters of pregnant sickle cell disease subjects in the Niger Delta Region, south of Nigeria. The study included twenty (20) pregnant sickle cell anemia subjects with average age of 27.4 years and twenty (20) apparently healthy (Hemoglobin AA) subjects with average age of 28.2 years. Their samples collection started when they registered for antenatal care at the clinics within the first trimester of pregnancy. The Enzyme Linked Immunosorbent assay (ELISA) method was used in the measurement of the hormones in the plasma of the subjects. The result showed a statistical significant reduction (P