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Buljevac, D., Flach, H.Z., Hop, W.C., Hijdra, D., Laman, J.D., Savelkoul, H.F., et al. (2002) Prospective Study on the Relationship between Infections and Multiple Sclerosis Exacerbations. Brain, 125, 952-960.
https://doi.org/10.1093/brain/awf098

has been cited by the following article:

• TITLE: Urodynamic Abnormalities in Patients with Relapsing Remitting Multiple Sclerosis

  AUTHORS: Alaaeldin Sedky Bekhit, Mohammed Saber-Khalaf

  KEYWORDS: Urodynamic, Bladder Dysfunction, Multiple Sclerosis

  JOURNAL NAME: World Journal of Neuroscience, Vol.8 No.4, October 25, 2018

  ABSTRACT: Background: Multiple sclerosis (MS) is a disease with wide variability in clinical presentation. Bladder dysfunctions are very common in MS patients. Early detection of bladder abnormalities is important to improve the outcome in MS patients. Objectives: The aim of this study is to evaluate the urodynamic detected bladder dysfunctions in relapsing remitting MS patients with mild or without lower urinary tract symptoms. Methods: This is a prospective study for 32 patients with relapsing remitting Multiple Sclerosis from January 2017 to June 2018. We included patients with mild or without lower urinary tract symptoms (LUTS) who had mild to moderate disability. Urodynamic studies were performed for all patients. Results: Urodynamic abnormalities were detected in 22 patients (68.75%). Detrusor overactivity (DO) was present alone in 8 patients (25%); DO combined with detrusor external sphincter dyssynergia in 8 patients (25%); DO with low compliant bladder and impaired contractility in another 4 patients (13%) while DO with low complaint bladder in 2 patients (6%). Bladder dysfunction was correlated to high disability score; longer duration of illness; frequent relapses and the presence of LUTS. Conclusion: Urodynamic abnormalities were found in 68.75% of our patients. This highlights the importance of urodynamic studies in the early evaluation of relapsing remitting Multiple Sclerosis.