TITLE:
Relationship between Voided Urine Volume and Urinary ATP in Healthy Volunteers
AUTHORS:
Kimio Sugaya, Saori Nishijima, Katsumi Kadekawa, Katsuhiro Ashitomi, Hideyuki Yamamoto
KEYWORDS:
Urinary ATP, Voided Urine Volume, Sex Difference
JOURNAL NAME:
Open Journal of Urology,
Vol.8 No.10,
October
16,
2018
ABSTRACT: Purpose: We examined the relationship between the urinary ATP level and the desire to void, voided urine volume, and urinary osmotic pressure. Materials and Methods: The subjects were 4 healthy volunteers (2 men and 2 women) without micturition disorders who were not taking any medications and had normal urinalysis findings. Over 2 - 3 days, they urinated into a clean cup a total of 20 times. The strength of the desire to void was classified (none, slight, moderate, or strong; scored from 1 to 4, respectively) and a voiding score was assigned at each urination, along with measurement of the voided volume, urinary ATP, urinary creatinine, and urinary osmotic pressure (one man). Results: Variation of the urinary ATP/creatinine ratio was large in both male and female subjects. The urinary ATP/creatinine ratio was lower in the 2 men compared with the 2 women. This ratio showed a significant negative correlation (R2 = 0.1577 and 0.1673, both p