TITLE:
Vitamin D: Level of Vitamin D3 in AFB Positive PTB Patients in Initial Diagnostic Phase
AUTHORS:
Anwar Ali Jamali, Jawaid Hussain Lighari, Shamasddin Shaikh, Ghulam Mustafa Jamali, Bhojo Mal Tanwani, Muhammad Aslam Channa, Ameer Ali Jamali, Muhammad Ali Suhail
KEYWORDS:
Pulmonary Tuberculosis, Vitamin D, Vitamin D Insufficiency, 25-Hydroxyvitamin D
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.6 No.4,
October
12,
2018
ABSTRACT: Background: A relationship among vitamin D and pulmonary tuberculosis. Objective: To conclude the occurrence of Vitamin D insufficiency in subjects suffering from pulmonary TB. Design: This was a cross sectional study. Setting: Current study was performed at department of medicine, Peoples Medical College Hospital Nawabshah starting from January 2017 to December 2017. Samples: 385 AFB positive subjects of pulmonary tuberculosis after achieving the criteria of selection were recruited. Material and Methods: After a brief discussion, the patients were characterized for variable evaluation such as age, gender, sputum AFB and duration of disease and presence of low vitamin D levels. Sputum AFB criterion was used for Data collection. Fasting blood samples were collected for analysis of vitamin D levels in all subjects of AFB positive pulmonary tuberculosis. Results: In 385 diagnosed patients with smear positive PTB, 273 (70.9%) males and 112 (29.1%) were female. Vitamin D levels were within normal or sufficient range in 134 (34.8%), below normal range in 251 (65.2%) cases (insufficient in 09.56% (24/251) and deficient in 90.43% (227/251) cases). Conclusion: Decreased levels of vitamin D were common in subjects with AFB smear Positive PTB cases.