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Ryan, J. and Heitmann, D.O. (2013) Anatomy of the Female Reproductive System. In: Decherney, A.N., Nathan, L., Laufer, N. and Roman, A.S., Eds., Current Obstetrics and Gynaecologic Diagnosis and Treatment, 11th Edition, MC Graw Hill Publishers, New York, 1-37.

has been cited by the following article:

• TITLE: Effect of Hyoscine Butyl Bromide on the Course of Labour

  AUTHORS: Dauda Deba Barau, Eyaofun Teddy Agida, Olatunde Onafowokan, Francis Olayemi Adebayo

  KEYWORDS: Hyoscine Butyl Bromide, Labour, Prolonged Labour

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.8 No.12, September 30, 2018

  ABSTRACT: Background: Hyoscine butyl bromide (Buscopan) is being used as an agent for reducing the duration of labour. There are however conflicting results on the effect of this agent on cervical dilation. Materials and Methods: This was an open label clinical trial of one hundred and thirty two (132) pregnant women in labour. Women were grouped to receive either 20 mg of hyoscine butyl bromide intramuscularly at the onset of active phase labour or placebo “Normal saline”. The main outcome measure was to compare the duration of first stage labour in the study and control groups as well as feto-maternal outcomes. Relevant data were collected using a proforma. The data were analysed using Statistical Package for Social Sciences (SPSS) version 20. Results: A total of 132 were randomised and 123 yielded for analysis. Of these 59 received hyoscine butyl bromide and 64 received placebo. There was no significant difference in the mean duration of active labour to second stage between the drug and placebo arms (312.5 versus 305.3 minutes, respectively, P = 0.788). The feto-maternal outcomes were similar between both arms. Conclusion: Hyoscine butyl bromide does not shorten the duration of labour in spontaneous labour. It also does not change feto-maternal outcomes.