TITLE:
Increased Risk of Bartonella Infections in Humans
AUTHORS:
Bogdanka Andric, Aleksandar Velkovski, Milan Jovanovic, Mosa Markovic, Mileta Golubovic
KEYWORDS:
Bartonellosis, Emerging, Diagnosis, Prognosis
JOURNAL NAME:
Open Journal of Clinical Diagnostics,
Vol.8 No.3,
September
28,
2018
ABSTRACT: Bartonellosis has emerging zoonoses of the Vector
Borne Diseases (VBD) complex. Progress in evolution and changes of causer, enabled
the expansion, and increased number of clinically manifest forms of disease
appearance of severe disseminated forms of infections and co-infections in
humans, difficult for diagnosis, therapy and prognosis. The Bartonellosis may
have a benign and self-limiting evolution in a host, or potentially fatal
infections. Etiological agents can provoke a granulomatous or an
angioproliferative histology damages. In severely immunodeficient cases
(pulmonary tuberculosis, carcinomatosis, HIV infection, patients who underwent
organ transplantation etc.), Bartonella infections can be difficult and often
with unpredictable course of the fatal prognosis. Present the large specter of
clinical manifestations: prolonged fever, erythema nodosum like syndrome, and
the other skin manifestations, sub-acute bacterial endocarditis, difficult
pulmonary disturbances, bacillary angiomatosis (BA) and hepatic peliosis (HP),
bacteriemia or a combination of these. In period 2007-2015 on Clinic for
Infectious Diseases in Podgorica, 25 cases with Bartonella infection were
diagnosed. In total sample, the most frequent were diagnosed CSD in 19 cases.
During 2015 in two cases with HIV/AIDS infection, BA was diagnosed, and in four
cases PH was diagnosed.