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Lv, Q., Yang, X., Wang, M., Yang, J., Qin, Z., Kan, Q., et al. (2018) Mitochondria-Targeted Prostate Cancer Therapy Using a Near-Infrared Fluorescence Dye-Monoamine Oxidase A Inhibitor Conjugate. Journal of Controlled Release, 279, 234-242.
https://doi.org/10.1016/j.jconrel.2018.04.038

has been cited by the following article:

• TITLE: Synthesis and Photophysical Properties of Novel Highly Stable Zero/Bis-Zero Methine Cyanine Dyes Based on N-Bridgehead Heterocycles

  AUTHORS: Ahmed I. Koraiem, Islam M. Abdellah, Ahmed M. El-Shafei

  KEYWORDS: N-Bridgehead Heterocycles, Cyanine Dyes, Zero/Bis-Zero Methine, Solvatochromic Behaviours

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.8 No.3, August 3, 2018

  ABSTRACT: Cyanine dyes of zero/bis-zero methine incorporating imid-azo(1,2-a)Pyridine (quinoline) or pyrazino(1,2-a)pyridine (quinoline) with stable C-N bond were synthesized using keto-oxime methylene C-link heterocyclic quaternary salts [1-phenyl-3-methyl-pyrazolino-4-keto-oxime-α-methylene-bis-pyridin-(quinoin)-1(4)-di-ium-iodide(ethiodide) salts and 1-phenyl-3-methyl-pyrazolino- 4-ketooxime-α-methylene-N-2-methyl-bis pyridin (quinoin)-1(4)-di-ium-iodide(ethiodide) salts]. Such heterocyclic precursors and related dyes were identified by elemental and spectral analyses. The absorption spectra properties of such dyes were investigated in 95% Ethanol to attempt and throw some light on the influence of such new heterocyclic nuclei and to compare or evaluate spectral behaviors. The absorption spectra of dyes in different pure solvents were examined in the visible region showing solvatochromism and the colour changes of dyes with solvents having different polarities. This permits a selection of the optimal solvent (fractional solvent) when such dyes are applied as photosensitizers. The spectral behavior of some selected newly synthesized cyanine dyes is observed in mixed solvents of different polarities and progressively increasing quantities of one solvent over the other were studied and showed an increase in the absorbance of CT band with increasing proportion of that solvent. Evidence for hydrogen bond formation between the solute molecules and solvent molecules allows measurement of certain energies such as hydrogen bonding, orientation, and free energies.