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Rolph, M.S., Zimmer, S., Bottazzi, B., Garlanda, C., Mantovani, A. and Hansson, G.K. (2002) Production of the Long Pentraxin PTX3 in Advanced Atherosclerotic Plaques. Arteriosclerosis, Thrombosis, and Vascular Biology, 22, e10-e14.
https://doi.org/10.1161/01.ATV.0000015595.95497.2F

has been cited by the following article:

• TITLE: The Relationship between Serum Pentraxin-3 Levels and Severity of Coronary Heart Disease

  AUTHORS: Mohamed Yahia, Omar S. Elmasry, Mai Abdel Ra’ouf

  KEYWORDS: Coronary Artery Disease, Pentraxin-3, SYNTAX Score

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.8 No.7, July 25, 2018

  ABSTRACT: Background: Clinical data suggested that pentraxin-3 is a biomarker for atherosclerosis due to its role in inflammatory processes since it exerts unfavorable effects on the course of atherosclerosis, stimulates plaque formation, and augments vascular inflammation. Objective: The aims of this study were to measure the level of serum pentraxin-3 in patients with suspected coronary artery disease (CAD) and to determine whether it was associated with the severity of CAD. Material and Methods: The serum pentraxin-3 level was measured by enzyme-linked immunosorbent assay in 80 patients who were referred for elective coronary angiography due to positive stress test results. SYNTAX score was used to determine the severity of CAD. Results: The study cohort consisted of 45 (56.25%) males and 35 (43.75%) females with a mean age of 55 ± 9.8 years. The mean serum pentraxin-3 level was 3.79 ± 1.38 ng/ml, and the mean SYNTAX score was 15.8 ± 11.3. A significant correlation was observed between pentraxin-3 level and SYNTAX score (r = 0.459, p - 32 or ≤22 (p = 0.002). Conclusion: The serum level of inflammatory marker pentraxin-3 is increased in patients with CAD and is correlated with the severity of CAD.