TITLE:
Malignant Melanocytic Matricoma and Criteria for Malignancy
AUTHORS:
Colton B. Nielson, Vladimir Vincek
KEYWORDS:
Pigmented Malignant Pilomatricoma, Malignant Melanocytic Matricoma, Melanocytic Matrical Carcinoma, Matricoma
JOURNAL NAME:
Open Journal of Pathology,
Vol.8 No.3,
July
13,
2018
ABSTRACT: Melanocytic matricoma is a very rare adnexal tumor that recapitulates the anagen hair follicle bulb. Few cases of malignant melanocytic matricoma have been reported, thus criteria for malignant potential have not been previously reviewed. We report a case of an 81 year old male that was originally diagnosed as atypical melanocytic matricoma. The site was re-excised with a small focus of residual tumor, but all margins were negative. The re-excision site healed without complication. However, two years after the original biopsy, a new 8 mm firm nodule appeared at the re-excision site, which was subsequently diagnosed as malignant melanocytic matricoma (MMM). In the following paper we will report a new case of MMM and review potential criteria that could be used in the future to establish malignant potential.