TITLE:
Primary Fallopian Tube Adenocarcinoma Discovered with the Vaginal Cytology: A Case Report with Pathological and Immunohistochemical Investigation
AUTHORS:
Tomoko Honda, Yuka Hiraku, Ryogo Aoki, Kenji Niwa, Naoki Watanabe, Takuji Tanaka
KEYWORDS:
Primary Fallopian Tube Carcinoma, Vaginal Cytology, Histopathology, Immunohistochemistry
JOURNAL NAME:
Open Journal of Pathology,
Vol.8 No.3,
July
13,
2018
ABSTRACT: Background: Primary fallopian tube cancer is an extremely rare gynecological malignancy. Aim: To discuss, through a case report, the diagnostic process by means of cytology immunohistochemistry. Case Presentation: A 47-year-old Japanese woman, who also had lung cancer, presented with enlarged para-aortic lymph node without any symptoms. Based on the vaginal cytology report suggestive of gynecologic malignant tumor (possibly fallopian tube adenocarcinoma), primary surgery comprised of total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. Histopathology and immunohistochemistry examinations revealed primary fallopian tube carcinoma with metastasis of para-aortic lymph node. She is free from recurrence and metastases 9 months after the surgery and chemotherapy. Conclusion: Although primary fallopian tube cancer is a rare gynecologic malignancy, vaginal cytology may be useful for detecting fallopian tube carcinoma.