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Scapoli, L., Palmieri, A., Martinelli, M., Pezzetti, F., Carinci, P., Tognon, M., et al. (2005) Strong Evidence of Linkage Disequilibrium between Polymorphisms at the IRF6 Locus and Nonsyndromic Cleft Lip with or without Cleft Palate, in an Italian Population. The American Journal of Human Genetics, 76, 180-183.
https://www.sciencedirect.com/science/article/pii/S0002929707625567
https://doi.org/10.1086/427344

has been cited by the following article:

• TITLE: Updating Genetics Polymorphisms of Non-Syndromic Clefts Lip-Palates

  AUTHORS: Amine Rafik, Sellama Nadifi

  KEYWORDS: Cleft Lip, Cleft Palate, Cleft Lip and/or Cleft Palate, Non-Syndromic, Genetics

  JOURNAL NAME: American Journal of Molecular Biology, Vol.8 No.3, July 13, 2018

  ABSTRACT: Introduction: Non-Syndromic Clefts Lip-Palates (NSCLP/CP) are most common congenital malformation in the world, with very important psychic and social impact. Formation of NSCLP/CP arises from the interaction of environmental and genetic factors. This paper provides a review of recent progress in defining the genetic causes of NSCLP. Methods: A literature review was conducted on the Medline data by searching for the following keywords: genes, non-syndromic cleft lip-palate, and genetics of clefts lip-palates, until January 2018. Results: Various genes are identified in different population and country, with the study using case parent’s trio. The aim of this study contributes to review relative gene which has been identify in non-syndromic cleft lip and palate, and to help to have a better understanding of the inheritance pattern of this pathology and the prevention of genetic disease. Conclusion: Although three major genes have been confirmed, the genetic research is necessary to provide an understanding of the pathophysiology of the clefts lip-palates.