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De Almodóvar, G.R., Ruiz, G.R., Rodríguez, A., Ortiz-Ferr ón, G., Redondo, J.M. and López-Rivas, A. (2003) TRAIL Decoy Receptor (TRAIL-R3) Is up Regulated by P53 in Breast Tumor Cell through a Mechanism Involving an Intronic P53 Binding Site.

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• TITLE: Quranic Verse No. 8 of Surat Al-Jumu’ah Leads Us to Describe Cancer and Determine its True Cause (Part-II)

  AUTHORS: Mahmoud Saad Mohamed El-Khodary

  KEYWORDS: Cancer Cause, Muc-1, Muc-4, Muc-16, Metalloprotenase Enzymes (MMPs) Bcl-2, Decoy-R3, NF-KB, Anti-Apoptotic Genes

  JOURNAL NAME: CellBio, Vol.7 No.2, June 1, 2018

  ABSTRACT: Cancer is cell fleeing from death by blocking the intrinsic and extrinsic programs of cell death. The six elements that shut down those programs are: muc-1, muc-4, muc-16, Bcl-2, MMPs and decoy R3. The nuclear factor-kappa B (NF-Kb) stimulates the expression of genes responsible for the production of those elements, which are used by cells to block those two programs. In other words, the nuclear factor kappa B (NF-KB) is responsible for blocking both programs. Therefore, the nuclear factor kappa B (NF-Kb) is the true cause of cancer.