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Forcheron, F., Cachefo, A., Thevenon, S., Pinteur, C. and Beylot, M. (2002) Mechanisms of the Triglyceride- and Cholesterol-Lowering Effect of Fenofibrate in Hyperlipidemic Type 2 Diabetic Patients. Diabetes, 51, 3486-3491.
https://doi.org/10.2337/diabetes.51.12.3486

has been cited by the following article:

• TITLE: Synthesis and Chiral Separation of Fibratol, Isopropyl 2-(4-((4-chlorophenyl)(hydroxyl) methyl)-phenoxy)-2-methylpropanoate

  AUTHORS: Amanda E. Kotheimer, Wahajul Haq, Ganesaratnam K. Balendiran

  KEYWORDS: Reduction, Chirality, Optical Activity, Fibrate

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.8 No.2, May 30, 2018

  ABSTRACT: Practical synthetic route for the formation of enantiomeric mixture of Isopropyl 2-(4-((4-chlorophenyl)(hydroxyl)methyl)phenoxy)-2-methylpropanoate (Fibratol 2a/b) from isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate (Fenofibrate 1) has been developed. Method has also been established for the chiral separation of enantiomers of Fibratol 2a/b that is synthesized using the route mentioned above. The optical activity determined for enantiomerically separated Fibratol (2a) and Fibratol (2b) are -5.2° and 8.0° which reflect their ability to rotate plane polarized light counterclockwise (levo) and clockwise (dextro), respectively.