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(a) P. J. Flory and J. J. Rehner, “Statistical mechanics of cross-linked polymer networks”, J. Chem. Phys., Vol. 11, 1943, pp. 512-520. (b) P. J. Flory and J. J. Rehner, “Statistical mechanics of cross- linked polymer networks II. Swelling”, J. Chem. Phys., Vol. 11, 1943, pp. 521-526.

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• TITLE: Cells Attachment Property of PVA Hydrogel Nanofibers Incorporating Hyaluronic Acid for Tissue Engineering

  AUTHORS: Kyu-Oh Kim, Yaeko Akada, Wei Kai, Byoung-Suhk Kim, Ick-Soo Kim

  KEYWORDS: Nanofiber, Electrospinning, Hydrogel, Poly(Vinyl Alcohol), Hyaluronic Acid, Cell Affinity

  JOURNAL NAME: Journal of Biomaterials and Nanobiotechnology, Vol.2 No.4, October 11, 2011

  ABSTRACT: In this work, we report the fabrication and cell affinity studies of the poly(vinyl alcohol) (PVA)/hyaluronic acid (HA) cross-linked nanofibers via electrospinning and post cross-linking. FT-IR and TGA analysis demonstrate that HA is not influenced by acid environment such as HCl vapor during cross-linking, and well incorporated into PVA nanofibers. Swelling behavior and cell adhesion of the PVA/HA hydrogel nanofibers are investigated and compared with pure PVA hydrogel nanofibers. It is expected that the nanofibrous PVA/HA hydrogel fibers could be a promising scaffold for cell culture and tissue engineering applications.