TITLE:
Optical Coherence Tomography Parameters in Preperimetric Open-Angle Glaucoma
AUTHORS:
Snezhina Stefanova Kostianeva-Zhelinska, Marieta Konareva-Kostianeva, Marin Atanassov
KEYWORDS:
Optical Coherence Tomography, Preperimetric Glaucoma, Retinal Nerve Fiber Layer, Ganglion Cell Complex
JOURNAL NAME:
Open Journal of Ophthalmology,
Vol.8 No.2,
May
21,
2018
ABSTRACT: Purpose: To evaluate the measurements of the peripapillary retinal neurofiber layers (RNFL) and the ganglion cells complex (GCC) obtained by Optical Coherence Tomography (OCT) in eyes with preperimetric open-angle glaucoma. Methods: One hundred and forty eyes of 75 patients (21 male and 54 female), 80 eyes with preperimetric glaucoma (PPG) (45 patients) and 60 normal eyes (30 subjects) were included in this study. Automated visual field examination was done to all participants using Humphrey field analyzer, program 30-2. The GCC thickness and peripapillary RNFL thickness were measured using RTVue-100 (Optivue, Inc., Fremont, CA). The areas under ROC (receiver operating characteristic)—curves (AUCs) were defined for all examined GCC and RNFL parameters. Results: GCC of the eyes with PPG was significantly thinner than GCC of the normal eyes: (89.58 vs 97.82 microns, P