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Ihara, Y., Toyokuni, S., Uchida, K., Odaka, H., Tanaka, T., Ikeda, H., Hiai, H., Seino, Y. and Yamada, Y. (1999) Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats a model of type 2 diabetes. Diabetes, 48, 927-932. doi:10.2337/diabetes.48.4.927

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• TITLE: Pancreas-protective effects of chlorella in STZ-induced diabetic animal model: insights into the mechanism

  AUTHORS: Amr Amin, Mohamed Lotfy, Doaa Mahmoud-Ghoneim, Ernest Adeghate, Mohamed A. Al-Akhras, Maryam Al-Saadi, Salam Al-Rahmoun, Rasheed Hameed

  KEYWORDS: Chlorella; Diabetes; Glucose; Insulin; Beta Cells.

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.1 No.3, August 31, 2011

  ABSTRACT: The aim of this study is to examine the effect of intragastric administration of chlorella (1 g/kg body weight) for a period of 30 days to treat normal and diabetic male Wistar rats. Diabetes was induced by intraperitoneal injection of streptozotocin (STZ) (60 mg/kg - 1 body weight). A significant (p