TITLE:
Successful Treatment of Adult Pleomorphic Rhabdomyosarcoma in the Posterior Left Femur: A Case Report
AUTHORS:
Barlian Sutedja, Abdul Muthalib, Ikhwan Rinaldi, Terawan Agus Putranto, Tjondro Setiawan, Diah Rini Handjari, Jubilate Edward I. Tambun, Reza Adiwidjaja
KEYWORDS:
Rhabdomyosarcoma, Pleomorphic, Adult, Multidisciplinary Approach, Multimodality Treatment, TACI, Cryosurgery, Surgery
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.9 No.4,
April
30,
2018
ABSTRACT: Introduction: Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma, but it represents only a small portion of soft tissue sarcoma in adult population. There is a treatment protocol based on Intergroup Rhabdomyosarcoma Study (IRS) that provides satisfactory results in treating RMS in children, but there is only limited evidence regarding the outcome and prognosis in extrapolating the IRS protocol to treat RMS in adults. We report a case of adult pleomorphic RMS treated with multidisciplinary approach and the results we have obtained. Case presentation: A 48-year-old woman was admitted in February 2011 due to a painful mass on her left thigh. Diagnosis of pleomorphic rhabdomyosarcoma was made by histopathology and immunohistochemistry. After multimodal treatment that includes Trans-Arterial Chemotherapy Infusion, Cryosurgery, and wide excision surgery, our patient remains disease-free as of the latest annual follow up examination on June 2017. Conclusions: The pleomorphic type of Rhabdomyosarcoma is very rare in adults and is often associated with a poor prognosis. In our case, a multidisciplinary approach with multimodal treatment provides excellent result, even after a routine follow up spanning through six years.