TITLE:
Contribution of Immunohistochemistry in the Diagnosis of Lymphomas
AUTHORS:
Daouda Kone, Yao Nicaise Atimere, Zana Ismael Coulibaly, Ulrich Acko, Sogbety Eric Diomande, Maimouna Toure, Pr Aissata Tolo
KEYWORDS:
Lymphomas, Immunohistochemistry, Histology, WHO Classification
JOURNAL NAME:
Open Journal of Blood Diseases,
Vol.8 No.1,
March
28,
2018
ABSTRACT: Objective: Making the interest of using immunohistochemistry clear in addition to histological test in the diagnosis of lymphomas. Methods: This is a retrospective study from January 2011 to June 2013 involving 18 cases of lymphomas collected in the teaching hospitals of Treichville and Yopougon. Results: 1) 38.88% diagnosis of LMNH B large-cell in histology against 38.88% LDGCB with IHC. 2) 11.11% diagnosis of LMNH small cell in histology against 11.11% with IHC. 3) 5.55% diagnosis of T lymphoma in histology against 27.77% diagnosis of T lymphoma with IHC. 4) 5.55% diagnosis of follicular lymphoma in histology against 11.11% diagnosis of LF with IHC. 5) 11.11% diagnosis of Burkitt lymphoma in histology against 5.55% diagnosis of LB with IHC. 6) 5.55% diagnosis of medullary hypoplasia in histology against 5.55% diagnosis of Hodgkin’s disease. Our results confirm the contribution of immunohistochemistry in the diagnosis of lymphomas in addition to histological test. This is striking, especially as there is 27.77% of T lymphoma with immunohistochemistry against only 5.55% with histology.