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Reid, R., Banerjee, S.S. and Sciot, R. (2002) Giant Cell Tumors. In: Fletcher, C.D.M., Unni, K.K., Mertens, F., Eds., World Health Organization Classification of Tumors. Pathology and Genetics of Tumors of Soft Tissue and Bone, IARC Press, Lyon, 309-313.

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• TITLE: Unusual Expansive Mass in the Thyroid Cartilage

  AUTHORS: Amaya Roldán-Fidalgo, Jose Ramón Secades, Javier Ibarra, Helena Sarasibar

  KEYWORDS: Giant Cell Tumor, Larynx, Thyroid Cartilage

  JOURNAL NAME: International Journal of Otolaryngology and Head & Neck Surgery, Vol.7 No.2, March 16, 2018

  ABSTRACT: Introduction: Giant cell tumor of the larynx is an uncommon entity with only 42 reported cases in the literature, of which 32 involved the thyroid cartilage. These tumors most commonly occur in the epiphysis of the long bones of female patients in the third decade. Case Report: We present a 57-year-old man with hoarseness and a growing anterior neck mass for the past 5 months. Endoscopic examination revealed a submucosal swelling of the left supraglottic area. CT and MRI of the larynx showed a large, expansive mass at the left thyroid cartilage. The anterior neck mass was biopsied and histopathological analysis showed mononuclear cells and homogeneously distributed multinucleated giant cells. A giant cell tumor of the larynx was suspected. The patient underwent a supracricoid subtotal laryngectomy. Conclusion: Giant cell tumor of the larynx is an uncommon entity, with very few cases reported in the literature. These tumors should be included in the differential diagnosis of a patient with hoarseness and anterior neck swelling. There is no consensus regarding the management, although surgical excision is the most frequently employed treatment with excellent outcomes.