TITLE:
Supersaturated Calcium Phosphate Rinse vs. Standard of Care for Mitigating Mucositis in Head and Neck Chemoradiation
AUTHORS:
Justin Brock, Chris Morris, Kathleen Hotze, Brian Pikkula
KEYWORDS:
Oral Mucositis, Health Care Cost, WHO OM Scale
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.9 No.3,
March
14,
2018
ABSTRACT: Introduction: Oral mucositis (OM) can have a significant impact on patients’ quality
of life, pain and treatment costs. Almost all patients receiving head and neck
chemoradiation develop OM. Patients and Methods: Twenty patients were
evaluated retrospectively for OM when undergoing head and neck chemoradiation.
The control, soda/salt rinse, was compared to a powdered supersaturated calcium
phosphate rinse (SSCPR), SalivaMAX. Results: The SSCPR group experienced
a delay in the onset of OM, which was not statistically significant, and a
marked reduction in peak OM that was statistically significant (p > 0.001). Conclusion: This
retrospective study demonstrates that a powdered SSCPR is a safe and effective
method of oral mucositis mitigation.