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Finny, D.J. (1952) Estimation of the Median Effective Dose-Response Curve. Chapter 3, Probit Analysis, Cambridge University Press, New York, 20-48.

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• TITLE: Synthesis and Antifungal Activity of Some New Fluorine-Substituted 4-Thiazolidinone Bearing 1,2,4-Triazinone

  AUTHORS: Layla A. Taib

  KEYWORDS: Synthesis, Fluorine, 4-Thiazolidinone, 1, 2, 4-Triazin Fungal

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.8 No.1, March 14, 2018

  ABSTRACT: Fluorine substituted 4-thiazolidinone 5 bearing 1,2,4-triazinone obtained from the condensation of 3-Amino-6(2’-aminophenyl)-1,2,4-triazin-5(4H)-one (2) with an aromatic aldehyde followed by cycloaddition with mercaptoacetic acid afforded the thiazolidinone (4), and treatment with ethyl trifluoroacetate. Structure of the products has been deduced from their correct elemental analysis and spectral measurements. The antifungal activity of the new fluorinated target also has been evaluated.