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Sola, E., Watson, H., Graupera, .I, et al. (2012) Factors Related to Quality of Life in Patients with Cirrhosis and Ascites: Relevance of Serum Sodium Concentration and Leg Edema. Journal of Hepatology, 57, 1199-1206.
https://doi.org/10.1016/j.jhep.2012.07.020

has been cited by the following article:

• TITLE: The Evaluation of Tolvaptan Therapy and Long-Term Prognosis in Hepatocellular Carcinoma with Refractory Ascites

  AUTHORS: Masaaki Shimada, Hiroaki Iwase, Noboru Hirashima, Masashi Saito, Hisashi Kondo, Noboru Urata, Satoshi Unita, Takashi Kondo, Daiki Tanaka

  KEYWORDS: Tolvaptan, Hepatic Ascites, Sarcopenia, Loop Diuretics, Long-Term Prognosis

  JOURNAL NAME: Open Journal of Gastroenterology, Vol.8 No.2, February 13, 2018

  ABSTRACT: We investigated Tolvaptan efficacy and long-term prognosis with focus on nutrition in 20 patients with refractory hepatic ascites in hepatocellular carcinoma (HCC). Bloating improved in 55% of patients, as determined using a Japanese version of the Support Team Assessment Schedule. Nutritional status improved with Tolvaptan treatment, based on the Controlling Nutritional Status score and Onodera’s prognostic nutritional index. Long-term prognosis was better in responders than in non-responders (mean survival time: 308 days vs. 97 days, p = 0.031). Tolvaptan was even effective in many patients with HCC, with additional improvement in long-term prognosis expected with improvement in the nutritional status.