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Trepat, X., Deng, L., An, S.S., Navajas, D., Tschumperlin, D.J., Gerthoffer, W.T., Butler, J.P. and Fredberg, J.J. (2007) Universal physical responses to stretch in the living cell. Nature, 447, 592-596.

has been cited by the following article:

• TITLE: Effect of deformation rate on the mechanical properties of arteries

  AUTHORS: Jorge O. Virues Delgadillo, Sebastien Delorme, Vincent Mora, Robert DiRaddo, Savvas G. Hatzikiriakos

  KEYWORDS: Mechanical Properties; Artery; Uniaxial & Biaxial Testing; Deformation Rate; Viscoelasticity; Constitutive Model

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.3 No.2, March 1, 2010

  ABSTRACT: Pig aorta samples were tested uniaxially and equi- biaxially at deformation rates from 10 to 200 %/s. Under uniaxial and biaxial testing, loading forces were reduced up to 20% when the deformation rate was increased from 10 to 200 %/s, which is the opp- osite to the behaviour seen in other biological tissues. A rate-dependent isotropic hyperelastic constitutive equation, derived from the Mooney-Rivlin model, was fitted to the experimental results (e.g. aorta specimens) using an inverse finite element technique. In the proposed model, one of the material par- ameters is a linear function of the deformation rate. The inverse relationship between stiffness and defo- rmation rate raises doubts on the hypothesized rel- ationship between intramural stress, arterial injury, and restenosis.