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Yao, J.C., Lombard-Bohas, C., Baudin, E., Kvols, L.K., Rougier, P., Ruszniewski, P., Hoosen, S., St. Peter, J., Haas, T., Lebwohl, D., Van Cutsem, E., Kulke, M.H., Hobday, T.J., O’Dorisio, T.M., Shah, M.H., Cadiot, G., Luppi, G., Posey, J.A. and Wiedenmann, B. (2010) Daily Oral Everolimus Activity in Patients with Metastatic Pancreatic Neuroendocrine Tumors After Failure of Cytotoxic Chemotherapy: A Phase II Trial. Journal of Clinical Oncology, 28, 69-76.
https://doi.org/10.1200/JCO.2009.24.2669
has been cited by the following article:
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TITLE:
Pancreatic Neuroendocrine Tumors in the 21st Century—An Update
AUTHORS:
Rani Kanthan, Jenna-Lynn Senger, Shahid Ahmed, Selliah Chandra Kanthan
KEYWORDS:
Neuroendocrine Tumors, Pancreatic, Unfathomable Neoplasm
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.8 No.13,
December
15,
2017
ABSTRACT: Pancreatic
neuroendocrine tumors (PNETs) are rare, reported to account for less than 1% - 2% of all pancreatic tumors. This, however, is likely an underestimation, as
improved radiologic techniques and heightened awareness have resulted in an
increase in the detection of incidentalomas, with estimations of true
prevalence as high as 10%. The term “PNET” is an umbrella name that encompasses
a heterogeneous group of neoplasms each with distinct clinical presentations,
diagnostic radiographic features, management principles, and tumor/patient
outcomes. In this context, accurate diagnosis is challenging, and management
guidelines remain unclear. A high degree of clinical suspicion is required for
best patient management. This manuscript provides an update on PNETs in the 21st century, in which we re-examine the terminology, epidemiology, classification,
etiopathogenesis, radiographic and histopathologic diagnostic features,
management for localized and metastatic disease, as well as a review of
features defining functional and non-functional PNETS, and finally deliberates
on the prognosis and predictive features of this unpredictable and largely
unfathomable neoplasm.