Article citationsMore>>

J.-M. Ku, M.-S. Yoo, H.-G. Park, S.-S. Jew and B.-S. Jeong “Asymmetric Synthesis of a,b-Epoxysulfones via Phase-Transfer Catalytic Darzens Reaction,” Tetrahedron, Vol. 63, 2007, pp. 8099-8103.

has been cited by the following article:

• TITLE: Phase Transfer Catalysis of Henry and Darzens Reactions

  AUTHORS: Layla Mhamdi, Hafedh Bohli, Younes Moussaoui, Ridha ben Salem

  KEYWORDS: Darzens, Henry, Phase Transfer Catalysis, Mechanism

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.1 No.3, September 28, 2011

  ABSTRACT: We describe in this work the influence of the addition of phase transfer catalyst in heterogeneous medium liquid/liquid on the output of the reactions of Darzens and Henry. It proves that the reaction of Darzens is favoured in the presence of low base such as K2CO3 and Et3N. Phase transfer catalysis is an efficient activation method in Darzens and Henry reactions. Thus, the Ethylene Diammonium Diacetate (EDD) has a comparable catalytic activity has that of quaternary ammonium salts in the reaction of Darzens.