TITLE:
Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles
AUTHORS:
Venkatapuram Padmavathi, Thunga Radha Lakshmi, Bhumireddy Chinnachennaiahgari Venkatesh, Konda Mahesh
KEYWORDS:
1-Aroyl-2-Styrylsulfonylethene, 1, 3-Dipolar Cycloaddition, Chloramine-T, Antimicrobial Activity
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.1 No.3,
September
28,
2011
ABSTRACT: A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.