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Kang, J., Rychahou, P.G., Ishola, T.A., Mourot, J.M., Evers, B.M. and Chung, D.H. (2008) N-myc Is a Novel Regulator of PI3K-Mediated VEGF Expression in Neuroblastoma. Oncogene, 27, 3999-4007.
https://doi.org/10.1038/onc.2008.15
has been cited by the following article:
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TITLE:
N-Myc Inhibition: Advances in Neuroblastoma Treatment
AUTHORS:
Md Kamrul Hasan
KEYWORDS:
Neuroblastoma, N-Myc, PI3K/mTOR, PARP1, PD-L1, HAUSP
JOURNAL NAME:
CellBio,
Vol.6 No.3,
September
30,
2017
ABSTRACT: Neuroblastoma (NBL) is one
of the most common solid tumors and around 15% of cancer mortality in children.
Amplification of the N-Myc proto-oncogene is strongly correlated with
advanced disease and poor clinical outcome in NBL. Recent studies described
that ubiquitin-specific protease 7 (USP7; also known as HAUSP) interacts with
N-Myc, induces deubiquitination and subsequent stabilization of N-Myc that
in-turn potentiates N-Myc
function, and treatment with the HAUSP inhibitor (P22077) blocked such effects.