Article citationsMore>>

Chihiro, M., Nagamoto, H., Takemura, I., Kitano, K., Komatsu, H., Sekiguchi, K., Tabusa, F., Mori, T., Tominnaga, M. and Yabuuchi, Y. (1995) Novel Thiazole Derivatives as Inhibitors of Superoxide Production by Human Neutrophils: Synthesis and Structure-Activity Relationships. Journal of Medicinal Chemistry, 38, 353-358.
https://doi.org/10.1021/jm00002a017

has been cited by the following article:

• TITLE: Facile Synthesis of Nitriles and Amides from Aldehyde over Heterogeneous Reusable Copper Fluorapatite (CuFAP) Catalyst under Neat Reaction Condition

  AUTHORS: Santosh S. Chavan, Mohsinkhan Y. Pathan, Taufeekaslam M. Y. Shaikh, Shafeek A. R. Mulla

  KEYWORDS: Heterogeneous, Recyclable, Nitriles, Amide, Aldehyde, Copper Fluorapatite

  JOURNAL NAME: Open Journal of Synthesis Theory and Applications, Vol.6 No.3, July 31, 2017

  ABSTRACT: A new robust heterogeneous, versatile, an environmentally benign, eco-friendly, recyclable CuFAP catalyst has been developed for the direct synthesis of nitriles and amides from aldehydes at 100°C for 6 h and 4 h, respectively, under neat reaction condition using hydroxylamine hydrochloride in the presence and the absence of tosyl chloride, respectively. Also the recyclability of catalyst as well as influence of solvents, additives on catalysts performance was investigated. The protocol can be considered as an alternative to conventional method for the synthesis of nitriles and amides in good to excellent yields. A highlight of our protocol is the easy separation of catalyst from reaction mixture, hence the catalyst is reused several times without significant loss of its catalytic activity.