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Koolhaas, J.M., Korte, S.M., De Boer, S.F., Van Der Vegt, B.J., Van Reenen, C.G., et al. (1999) Coping Styles in Animals; Current Status in Behavior and Stress-Physiology. Neuroscience & Biobehavioral Reviews, 23, 925-935.
https://doi.org/10.1016/S0149-7634(99)00026-3

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• TITLE: The Influence of Behavioral and Psychological Symptoms of Dementia on the Autonomic Nervous System

  AUTHORS: Daisuke Kimura, Ken Nakatani, Masako Notoya, Aiko Imai, Taro Ohtoshi

  KEYWORDS: BPSD, Autonomic Nervous System Activity, Structural Equation Modeling Analysis

  JOURNAL NAME: World Journal of Neuroscience, Vol.7 No.4, November 23, 2017

  ABSTRACT: Stress is one of the most potent of many factors that can cause expression of behavioral and psychological symptoms of dementia (BPSD). Stress can also increase autonomic nervous activity. This study aimed to examine the relationships between BPSD and autonomic function in the elderly with dementia. We recruited 35 participants diagnosed with dementia from nearby geriatric health service facilities. The Neuropsychiatric Inventory was used for the evaluation of BPSD, and a TAS 9 VIEW (manufactured by YKC) was used for the heart rate variability analysis to measure autonomic nervous system activity. We constructed a model in which the autonomic nervous system comprised a category and performed a structural equation modeling analysis to calculate the standardization coefficient and correlation coefficient for each factor. The results showed that the influence of BPSD resulted in suppression of sympathetic and enhancement of parasympathetic nervous system activity.