TITLE:
Epidemiological, Clinical, Biological, Therapeutic Features and Outcome of Congenital Malaria at the Borgou Regional University Teaching Hospital (CHUD-B) in Benin in 2015
AUTHORS:
Godonou Gratien Sagbo, Alphonse Noudamadjo, Joseph Agossou, Julien Didier Adedemy, Awade Achille Obossou, Djewessi Saturnin Lokossou
KEYWORDS:
Congenital Malaria, Outcome, Benin
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.7 No.4,
November
21,
2017
ABSTRACT: Background: The prevalence of congenital malaria is getting more and more
significant in Sub-Saharan Africa where is a malaria-endemic area. This study aimed to identify the clinical and
therapeutic features as well as the outcome of congenital malaria in CHUD-B in
2015. Method: It was a cohort and descriptive study with analytical
purpose, carried out in the Mother and Child Department which includes the
Gynecology & Obstetrics and Pediatric Unit of CHUD-B. The study target
population consisted of all the infants born in the CHUD-B as well as their
mothers. The main variable was the presence of congenital malaria. The independent
variables were those related to clinical, therapeutic features and outcome. Results:
In the study, among the 300 newborns registered, 57 carried congenital malaria i.e. a prevalence of 19%. 171 (57.0%) of them were males versus 129 (43.0%) females. Among the 281 mothers involved, 48 presented with
malaria in pregnancy i.e. a
prevalence of 17.0%. At the end of this research work, the factors
associated with congenital malaria were
fever in the 3rd quarter and malaria in pregnancy in the mother. Conclusion: Nearly one out of five infants born in the CHUD-B was carrier of congenital malaria and approximately one out six mothers presented with malaria
detection during pregnancy. A method based on Polymerase Chain Reaction (PCR) should be implemented during the diagnosis
in order to confirm malaria cases among both newborns and mothers.