TITLE:
Severity of the Rheumatoid Arthritis in Sub-Saharan Africa: Study of 403 Senegalese Observations
AUTHORS:
Moustapha Niasse, Baïdy Sy Kane, Abdoul Aziz Ndiaye, Awa Cheikh Ndao, Boundia Djiba, Seynabou Fall, Ngoné Diaba Diack, Fatimata Bintou Sall, Michel Assane Ndour, Nafy Diagne, Atoumane Faye, Biram Codou Fall, Souhaïbou Ndongo, Abdoulaye Pouye
KEYWORDS:
Rheumatoid Arthritis, Africa South of the Sahara, Senegal
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.7 No.4,
November
20,
2017
ABSTRACT: Introduction: We
assess the severity of the rheumatoid arthritis in a Senegalese African black
population. Patients and methods: It is a retrospective study achieved in the service of Internal Medicine of
Aristide Le Dantec teaching hospital of Dakar between January 2005 and
December 2016 in patients suffering from rheumatoid arthritis. We specified for
every patient the predictive data of severity of the rheumatoid arthritis. Results: Four hundred and three patients have been gathered (39 men and 364 women), with
the mean age of 45.8 years. An active tobacco addiction was noticed in 10
patients. The diagnostic delay was on average of 72 months. Characteristic
articular deformations were noticed in 215 patients (53.3%). They were
correlated to male (p = 0.038), to age (p = 0.001) and to the activity of the
rheumatoid arthritis (p = 0.0445). Systemic manifestations have been observed
in 213 cases (52.9%), particularly anemia (50.8%). They were correlated to the
anti-CCP antibodies (p = 0.047). The ESR was increased at the first hour in
84.4% of cases (median: 43 mm; extreme: 1and 160). CRP was elevated in 63.71% of cases
(median of 12 mg/l; extreme: 1 and 384). The rheumatoid factor was positive in
57.6% of the cases. The anti-CCP antibodies
were present in 89.2% of the cases. Articular
erosions were objectified in all cases. A DAS 28 superior to 5.1 was noticed in
71% of cases. Conclusion: The rheumatoid arthritis was severe in our
study.