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Shimshoni, J.A., Bialer, M., Wlodarczyk, B., Finnell, R.H. and Yagen, B. (2007) Potent Anticonvulsant Urea Derivatives of Constitutional Isomers of Valproic Acid. Journal of Medical Chemistry, 50, 6419-6427. https://doi.org/10.1021/jm7009233

has been cited by the following article:

• TITLE: Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives

  AUTHORS: Fanny Araceli Cabrera-Rivera, Luis Gabriel Hernández-Vázquez, Patricia Flores-Sánchez, Maria Durán-Galván, Jaime Escalante

  KEYWORDS: Microwave, Decarboxylation, Malonic Acid Derivatives, Solvent-Free, Catalyst-Free, Green Chemistry

  JOURNAL NAME: Green and Sustainable Chemistry, Vol.7 No.4, November 15, 2017

  ABSTRACT: It has been found that microwave assisted decarboxylation of malonic acid derivatives can be achieved under solvent-free and catalyst free conditions. This new method produces the corresponding carboxylic acid in a pure manner and with a high yield in a very short reaction time: 3 - 10 min. In general terms, the condition under which this reaction is carried out accelerates the decarboxylation significantly of a series of disubstituted malonic acid derivatives, and makes this new process efficient, easy and environmentally friendly.