TITLE:
Neurofibromatosis Type 1 in Four Children Cases
AUTHORS:
C. Mammad, N. Mekaoui, F. Z. Ouadghiri, K. Mammad, B. S. Benjeloun Dakhama
KEYWORDS:
Neurofibromatosis Type 1, Children, Café au lait Spots, Lentiginous
JOURNAL NAME:
Neuroscience and Medicine,
Vol.8 No.3,
September
28,
2017
ABSTRACT: Neurofibromatosis Type 1 (NF-1 or Von Recklinghausen disease) is an autosomal
dominant genetic disease, characterized by an extreme variability of its
clinical expression which is also found in the same family. Our work focuses
on the exploitation of four cases of patients with NF-1 who were enrolled in
the paediatric neurology consultation at Rabat Children’s Hospital. They are
two infants and two children. Otherwise the diagnosis was made in front of
the existence of café au lait and lentiginous spots in two boys, also the existence
of café au lait spots and abnormalities in brain imaging in two girls.
Thus an evolution was marked by a favorable outcome for three patients and
neurological sequelae in one patient.