TITLE:
Effect of Dimethoate on Object Recognition Memory in Wistar Rats and Essay of Treatment with Nettle
AUTHORS:
Majda Samih, Pacôme Kouadio N’Go, Sabah Belaaouja, Amina Ouazzani Touhami, Ahmed Omar Touhami Ahami
KEYWORDS:
Dimethoate, Dioic Nettle, Acetylcholinesterase, Chelation, Memory
JOURNAL NAME:
Journal of Behavioral and Brain Science,
Vol.7 No.9,
September
25,
2017
ABSTRACT: Pesticides were economically important chemicals in agriculture. Their use has permitted agricultural progress, through the eradication of harmful insect and the fight against vectors of disease. However, several studies question the beneficial effects of organophosphorus compounds, showing that their deregulated use causes various problems of environmental pollution and human health. The present study shows that chronic exposure to a subtoxic dose of dimethoate is likely to affect cognitive and behavioral functions of rats (both males and females). Our results show that exposure to dimethoate affects both short and long-term memory capacities. The short-term memory results are more pronounced. Treatment with nettle extract allowed a significant improvement in cognitive and behavioral performance of the rats after their exposure to dimethoate.