TITLE:
Evaluation of D-Dimer Level in Sudanese Patients with Chronic Liver Disease in IbnSina Hospital
AUTHORS:
Rehab Abdul Kareem Ahmed Al-Basheer, Amira Ahmed Khalid Humeida
KEYWORDS:
Chronic Liver Disease, Coagulation, D-Dimer, Sudan
JOURNAL NAME:
Open Journal of Internal Medicine,
Vol.7 No.3,
September
14,
2017
ABSTRACT: Background: Chronic liver disease is a disease process of the
liver that involves a process of progressive destruction and regeneration of
the liver parenchyma leading to fibrosis and cirrhosis chronic liver disease
refers to disease of the liver which had lasted over a period of 6 months. This
study was conducted to evaluate the D-dimer levels among Sudanese patients with Chronic Liver Diseases. Materials and Method: In IbnSina hospital, Khartoum state, Sudan, a case control study was conducted.
For this study, 100 participants were selected, 70 of them were patients known
diagnosed by chronic liver diseases as a test group. Other 30 participants were
normal healthy individual as control group. The plasma D-dimer level was
measured by using MINDRAY auto analyzer BS 380). Results: In this study,
the plasma D-dimer level has statistically significantly higher in chronic
liver diseases patients (mean ± SD 0.634 ± 0.215 ug/l) compared to normal healthy control group (mean
± SD 0.223 ± 0.077 ug/l) with P value 0.000. Conclusion: The present study revealed
that the D-dimer levels were statistically significant higher in chronic liver
diseases patients.